Availability: In Stock (25 packs)
Active Ingredient: Tinidazole
Manufacturer: Ranbaxy Laboratories Ltd.
Disease(s): Infection Of The Intestines Or Vagina / Sexually Transmitted Infections.
Tinidazole is used as an antiprotozoal drug with antibacterial features. It is often recommended for toxocariasis, giardiasis, ascariasis, as well as to prevent infection by anaerobic infections.
Instructions for use
According to the medical classification, Tinidazole refers to drugs that have an antiprotozoal, antimicrobial effect. The product is produced by Russian pharmaceutical companies Ozone, Biocom, Akrikhin. Check out his instructions.
The drug exhibits antibacterial activity, therefore, refers to antibiotics. It is active against trichomonads, giardia, bacteroids, clostridia, fusobacteria, peptococci, peptostreptococci. The active substance exhibits a lipophilic effect, penetrates into microorganisms, is restored by nitroreductase, which leads to inhibition of synthesis and damage to the structure of DNA.
The tablets have high absorption, 100% bioavailability, are combined with plasma proteins by 12%. They reach a maximum concentration in the blood after 2 hours, penetrate the membrane of the brain. The metabolism of the drug is carried out by the liver, pharmacologically active hydroxylated derivatives are formed that inhibit the growth of anaerobes and enhance the action of the active component. The half-life of the drug is 13 hours, it is excreted with bile, kidneys, and again absorbed by the renal tubules.
Instructions for use indicate diseases in which the drug can be used:
- endometritis amoebiasis of the liver form;
- Helicobacter pylori infection eradication, gastric ulcer;
- prevention of postoperative infections caused by anaerobes.
Men are not allowed to use Tinidazole if there are the following contraindications:
- violation of blood formation;
- organic diseases of the central nervous system;
- intolerance to the components of the composition, derivatives of 5-nitroimidazole.
How to use Tinidazole
Tablets are taken by men inside, with trichomoniasis, giardiasis, a dose of 2 g (4 pcs.) Once a day is prescribed. With intestinal amoebiasis, 2 g per day is prescribed for a course of 2-3 days, with amoebic process of the liver – 4.5-12 g per course (initial dose of 1.5-2 g per day for 3 days, if necessary, repeated up to 6 days).
In the treatment of infections caused by anaerobes, on the first day, take 4 g of the drug once, then 1 g once or in two divided doses for 5-6 days. For the prevention of postoperative infections, 4 tablets are taken once 12 hours before surgery.
If treatment continues for more than a week, monitoring of the blood picture is necessary. Other special instructions from the instructions:
- In the treatment of genital trichomoniasis at the same time you need to treat a sexual partner.
- During therapy, you need to refrain from controlling mechanisms and driving vehicles, because the rate of reactions decreases.
Tinidazole and alcohol
Doctors do not recommend taking tablets with alcohol, because this leads to the appearance of disulfiram-like reactions. Additionally, the liver is loaded, the effect of ethanol is enhanced, palpitations, difficulty breathing, vomiting, drop in blood pressure, chills, fever are manifested.
Tinidazole may cause side effects. The instruction names possible symptoms:
- dark urine;
- vomiting, loss of appetite, diarrhea, dry mouth, metallic taste;
- cramps, headache, weakness, dizziness, neuropathy, fatigue, dysarthria, locomotor ataxia;
- urticaria, pruritus, rash, angioedema; transient leukopenia.
Cases of drug overdose are not described. If the dose is exceeded, symptomatic treatment is indicated, there is no specific antidote. It is necessary to rinse the stomach, undergo a dialysis procedure to remove excess medicine.
Tinidazole or Metronidazole - which is better
The drug with the same active substance, Metronidazole, is also used to treat infections caused by anaerobes and simple microorganisms. Unlike Tinidazole, it can be used for leukopenia, but has more side effects. The mechanism of work for the funds is the same, the doctor should decide what is best for the patient.
Where to buy Tinidazole
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